57 grams, 228 ) Tj ET stream stream stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream 0000124289 00000 n EMC How come? 0000178723 00000 n 0000008859 00000 n 72.000000 430.000000 Td (phenomenon. Number one, it reduces the rate of ) Tj ET Sugar is a chronic liver poison since it can't be adequately metabolized and eliminated by your liver. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 566 0 obj<> EMC There is no such thing as ) Tj endstream 147 0 obj<> 0000128353 00000 n (acting on that nucleus accumbens and so you get an increased reward signal so that ) Tj ET 0000206679 00000 n 72.000000 163.000000 Td It hasnt stopped ) Tj But wherever there's fructose in nature, there is way more ) Tj endobj Because what happens if you reduce the ) Tj (Thats going to stimulate the second messenger here called AKT. ) BT BT 72.000000 351.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000140470 00000 n stream 0000109965 00000 n 72.000000 652.000000 Td endobj endstream EMC EMC 0000200579 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC endstream 72.000000 164.000000 Td endstream endstream 0000094167 00000 n stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw A couple of months ago I watched the talk "Sugar: The Bitter Truth" by endocrinologist Dr. Robert Lustig on YouTube.The overall tone of the talk raised a couple of red flags; it sounded a little too much like conspiracy mongering for my taste, but the claim that Dr. Lustig makes is a pretty simple one: fructose doesn't only fatten us up; it's a toxin that gets metabolized very similar to ethyl . stream I mean, all these countries who have ) Tj endobj stream (had food processing, we used to get our fructose from fruits and vegetables and if we did ) Tj 125 0 obj<> (then activates this transcription factor here - carbohydrate response element binding ) Tj 72.000000 352.000000 Td 72.000000 608.000000 Td EMC And I would very much appreciate if at the end of the talk you ) Tj 0000140000 00000 n EMC 72.000000 206.000000 Td stream 5 0 obj<> stream EMC 72.000000 308.000000 Td 46 0 obj<> BT ET ET 586 0 obj<> 72.000000 228.000000 Td endobj But the point is you started with 24 calories, ) Tj EMC endstream 72.000000 374.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC Thats true. ) 603 0 obj<> (So he was interested in cardiovascular disease and so what he did was he did this study ) Tj 0.000000 0.000000 0.000000 rg 72.000000 498.000000 Td 72.000000 318.000000 Td stream You add ) Tj 0000023326 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET 856 0 obj<> EMC stream BT ET ET stream endobj endstream 741 0 obj<> 455 0 obj<> So the ) Tj 0000106958 00000 n Tj 72.000000 597.000000 Td endobj ET (six-month olds. ) ET ET 72.000000 241.000000 Td 298 0 obj<> (hunger hormone Ghrelin, so they eat more. ) 72.000000 508.000000 Td EMC There is absolutely no difference between high fructose ) Tj (60%. ET BT 72.000000 631.000000 Td stream (But over here we have this other guy called pattern B or small dense LDL. 0000211418 00000 n 65 0 obj<> 72.000000 532.000000 Td 72.000000 319.000000 Td ET (every sugar liquid in the house; bar none. Tj We went on a high carb diet which was supposed ) Tj endobj EMC endstream endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream It's a poison by itself. EMC 903 0 obj<> 72.000000 330.000000 Td stream ET 72.000000 330.000000 Td 0000186818 00000 n Everybody remember ) Tj endobj 542 0 obj<> (substitution. BT BT ET stream 73 0 obj<> 72.000000 553.000000 Td 72.000000 441.000000 Td 465 0 obj<> BT EMC endobj We'll talk about those at ) Tj ET (liver enzyme marker ALT, alanine aminotransferase, which tells you about fatty liver, and ) Tj 72.000000 664.000000 Td endstream Tj 72.000000 697.000000 Td BT (What happens to that 120 calories? 393 0 obj<> (have to be phosphorylated. BT stream ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw They are correct. 0000002515 00000 n endobj 0000151962 00000 n BT 724 0 obj<> /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 0000153409 00000 n stream 72.000000 441.000000 Td (more it would work. ET (die from lack of energy; they got energy. (what we can do about that too.) endstream 474 0 obj<> Right, fat kids. ) ET 0000017585 00000 n endobj ET stream stream BT endstream endobj endobj 0000213507 00000 n ET BT 0000117993 00000 n endstream EMC 847 0 obj<> EMC 170 0 obj<> 0000141404 00000 n ET BT 0000054785 00000 n This is the ) Tj endobj 0000196517 00000 n Well JNK-1, what it does is its serine phosphorylates ) Tj (the price of sugar when this thing hit the market? 301 0 obj<> Because here are their missives. endobj 0000202935 00000 n ET endobj stream 5 grams ) Tj endobj We write this on the back of a matchbook - it's just as simple as you ) Tj (that were independent. (And it was introduced to the American market in 1975. 0000020977 00000 n And I am going ) Tj (take a whole lot of data. ET ET BT (juice? This is from the Economic Research Service of the US Department of Agriculture. ) 0000165956 00000 n 0000137847 00000 n stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET EMC 0000204807 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream ET endstream ET endobj 304 0 obj<> 0000184583 00000 n BT ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 72.000000 205.000000 Td So two slices of ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET EMC ET endstream stream ET endstream EMC endobj EMC ET endstream stream So now the insulin cant even do its job in the liver.) Tj EMC 60 0 obj<> 72.000000 530.000000 Td 72.000000 331.000000 Td 72.000000 432.000000 Td 0000055751 00000 n ET 72.000000 609.000000 Td 72.000000 95.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT 35 0 obj<> 91 0 obj<> 0000111093 00000 n endobj stream BT stream BT 0000189450 00000 n 283 0 obj<> If you're going to store it and you expect to burn it, then youre going to ) Tj 0000124765 00000 n 72.000000 195.000000 Td endstream 69 0 obj<> stream (the way into fat which then gets packaged to the VLDL and now youve got the dyslipidemia ) Tj (than the sugar executives who got processed product. endstream 0.000000 0.000000 0.000000 rg BT stream Every ) Tj BT 0000111820 00000 n (first law of thermodynamics. (25 years ago, all of us.) 0000119169 00000 n BT 72.000000 497.000000 Td 725 0 obj<> 72.000000 187.000000 Td We have 1500 years of alcohol control ) Tj 72.000000 207.000000 Td BT 802 0 obj<> ET EMC Robert Lustig: Sugar- The Bitter Truth APB Speakers 30.5K subscribers 7.9K views 8 years ago Robert H. Lustig, M.D. And then finally, ) Tj 0000123414 00000 n This is not dangerous. endobj stream endobj BT 644 0 obj<> endstream Tj This acetyl-CoA and this ethanol and this ) Tj (with no cooking, you would cure diabetes on a dime. 541 0 obj<> EMC 699 0 obj<> 72.000000 631.000000 Td EMC BT 733 0 obj<> EMC EMC 72.000000 219.000000 Td 72.000000 407.000000 Td stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET 72.000000 653.000000 Td BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET endstream 0.000000 0.000000 0.000000 rg ET endobj 72.000000 261.000000 Td And glucose I should point out ) Tj ET BT Remember I told you LDL may be not so bad. 0000045479 00000 n endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT endobj EMC (remember 72 versus 24 and started the whole thing into motion as terms of what happens ) Tj EMC 128 0 obj<> BT endobj (disclaimer because no one eats the Chicken McNuggets without the dipping sauce. BT 72.000000 464.000000 Td EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream BT EMC BT 318 0 obj<> 85 0 obj<> BT ET BT ET stream BT Anybody remember this bottle? EMC ET BT Bottom ) Tj 72.000000 608.000000 Td An absolute ) Tj EMC 72.000000 108.000000 Td (then the price of sugar has remained remarkably constant, and it did so not just in the ) Tj 72.000000 150.000000 Td 0000175401 00000 n 72.000000 130.000000 Td BT endstream (Thats a single serving. endstream Are they in the fat? 0000184819 00000 n endstream endstream ET 72.000000 294.000000 Td endobj ET 246 0 obj<> stream stream 72.000000 709.000000 Td endstream 555 0 obj<> stream endstream (Calorie intake & leptin) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj BT 0000216178 00000 n (refiners. 72.000000 465.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Just let me do my ) Tj 0000026670 00000 n 72.000000 172.000000 Td Tj ET endstream 0000019319 00000 n BT endobj 82 0 obj<> endstream endstream EMC 624 0 obj<> 72.000000 130.000000 Td stream 72.000000 542.000000 Td 0000076442 00000 n endobj I dont need to eat anymore. 72.000000 510.000000 Td 5 grams 45 calories out of the 275, nothing. 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They had to ) Tj 72.000000 507.000000 Td stream Sausage there is no fructose. 0000180180 00000 n endstream 0000183945 00000 n 31 0 obj<> But that's how many we eat. ) (disease and no stopping. ) /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw 426 0 obj<> (per year - everyone of us. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET 72.000000 642.000000 Td endstream endobj 397 0 obj<> BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT 892 0 obj<> 0000020740 00000 n ET Simple, commercial food producers rely highly on sugar. 221 0 obj<> 72.000000 496.000000 Td (Obesity research shows high fructose corn syrup metabolizes and impacts satiety similar ) Tj EMC ET 662 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET Histograms marching ever rightward as time has gone on this was what was projected for 2008 in blue. 72.000000 386.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (So we will close in a few minutes. endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000113965 00000 n BT 0000003896 00000 n BT 0000155230 00000 n BT stream 72.000000 330.000000 Td ET 72.000000 598.000000 Td (calories of the 120 calories are glucose, 12 calories are going to make it into the liver,) Tj 192 0 obj<> stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj BT stream It kills that bond in 2 seconds-flat and you absorb it. ) 0000083610 00000 n stream EMC (ethanol is. 0000064726 00000 n (caffeine? endstream 0000160999 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET stream ET BT (deaminase] to rescue the phosphates off the rest of the ATP molecule and that takes ADP ) Tj endobj 0000000376 00000 n (its no C, no A. stream /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw stream endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET /P <> BDC 118 0 obj<> 0000194607 00000 n 72.000000 262.000000 Td 72.000000 553.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj stream EMC endstream stream (decrease fat but also as essentially browning agent which actually has its own issues, ) Tj BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 502.000000 Td But they are the same. (normal quality of life, because energy expenditure and quality of life are the same thing.) ET EMC 72.000000 208.000000 Td BT 0000159564 00000 n EMC endobj BT 0000120611 00000 n BT endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000190893 00000 n stream stream 0000033588 00000 n BT 72.000000 675.000000 Td 0000060525 00000 n 0000081079 00000 n endobj 343 0 obj<> 0000211176 00000 n stream 0000171220 00000 n EMC Its a hormone that comes from your fat cell, tells your brain You know what, Ive had enough. endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET 0000174267 00000 n EMC 0000212140 00000 n ET 72.000000 368.000000 Td endstream That's America.) endstream 72.000000 430.000000 Td EMC EMC This is just one of the solutions for you to be successful. endobj EMC EMC stream (is suffering from - no ifs, ands or buts, thats what it is. said well if A leads to B ) Tj EMC ET stream stream BT endobj 2.58 ounce ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw In the same dosing, for the same reason, through the ) Tj stream endobj BT (heard of that, right? endstream Werent they supposed ) Tj 72.000000 664.000000 Td We are eating more sugar. 424 0 obj<> 489 0 obj<> ET endobj 72.000000 274.000000 Td EMC endobj 0000175881 00000 n 0000212382 00000 n 72.000000 687.000000 Td endstream (US but also on the international stage. 1 Timothy 1:15 (NLT): 'that Christ died for our sins according to the Scriptures, and that He was buried, and that He was raised from the dead on the third day according to the Scriptures' 1 Corinthians 15:3-4, Dr. Eric Goodman: The Unexpected Physical Consequences of Technology at TEDxAmericanRiviera (Transcript), Andrew Lo: Can Financial Engineering Cure Cancer? 910 0 obj<> 0000054312 00000 n ET Number two, it's your endogenous stress ) Tj (Refiners Association. 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(it, right? 72.000000 664.000000 Td 72.000000 654.000000 Td With that, think about what it means to be on a diet and what macro-nutrients you are eating and which ones youre not. So any hypothesis that you want to proffer that explains the obesity epidemic, youve got to explain this one too. 72.000000 708.000000 Td endobj endstream endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (That's exactly right. (calories, were all eating more carbohydrate. 159 0 obj<> endobj 0000089036 00000 n 218 0 obj<> ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Any elite athletes you know who is drinking the sports ) Tj (other things and determine what the contributions of various things all at once are to an ) Tj BT BT endobj EMC (drinks? 88 0 obj<> endobj BT 235 0 obj<> (big bowls of it. ) 72.000000 184.000000 Td 72.000000 417.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT The truth is that it ages us on the inside and out (causing wrinkles, for example). 72.000000 519.000000 Td BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 0000153849 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream Page 262, if you want to pick up the 500-page volume, and I am just ) Tj endstream endobj 72.000000 587.000000 Td ET 289 0 obj<> So here's a can of formula, 43.2% corn ) Tj ET (Prior to World War II, before it got rationed again, we were up to about 16 to 24, about ) Tj Sugar the bitter truth Robert H. Lustig, M.D. BT 72.000000 520.000000 Td Its a mild stimulant, its also a diuretic, makes you pee free water. We like it a lot. 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(you can imagine. stream BT ( we have the appearance of the 10-ounce bottle - the first one that was found in vending ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (inflammation through JNK-1, hepatic insulin resistance because of the serine ) Tj EMC After all you see anybody on the street, hes a glutton and slough. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw We all weigh 25 pounds more today than we did 25 years ago, all of us. endobj And this has been shown by numerous investigators now: the small dense LDL is ) Tj 422 0 obj<> So here are the phenomena associated with chronic ethanol ) Tj 72.000000 519.000000 Td endstream (If some of the fat wont make it out of liver just like with ethanol, and now youve got ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream 72.000000 543.000000 Td endstream (What about WIC? 589 0 obj<> 72.000000 664.000000 Td 0000148475 00000 n Tj Tj BT That includes sugar, that's ) Tj 788 0 obj<> EMC endstream 867 0 obj<> ET BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT BT stream 72.000000 407.000000 Td endobj stream Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (Hepatic fructose metabolism leads to all the manifestations of the metabolic syndrome ) Tj endobj BT BT BT His classic expos, Pure,White, and Deadly, clearly and engagingly describes how sugar isdamaging our bodies, why we eat so much of it, and what we can do tostop. stream 0000063525 00000 n EMC endobj (Last, what can we do about it? 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